1 Capsule daily · with food · morning or with lunch
Why with food? — Vitamin D3 is fat-soluble — absorbed significantly better when taken with a meal containing dietary fat. Morning or lunch dosing is preferred over evening because the small B-vitamin content can affect sleep onset in sensitive adults.
Why one capsule daily, not split doses? — B12 and D3 have long enough half-lives in the body that once-daily dosing is sufficient for maintenance. Folate's effect on methylation is a daily process; consistent daily intake matters more than timing precision.
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Safety & Competition Notes
- No WADA Prohibited Substances
- Vegan (HPMC capsule shell)
- Free from soy, dairy, sugar, nuts, gluten, artificial colours, fillers, preservatives
Pregnancy: Folate is critical for foetal neural development; consult your gynaecologist for the right total daily folate intake during pregnancy. This product contributes 300mcg DFE of active folate — your physician may recommend additional folate during the first trimester.
Prescription medication interactions: Methotrexate (used for cancer and autoimmune conditions) interacts with folate — consult your physician. Metformin (diabetes) can reduce B12 absorption; supplementation is often beneficial but doses should be reviewed.
Already taking a multivitamin? Most multivitamins contain B12 and D3 at lower doses with the cheaper forms (cyanocobalamin and folic acid). Taking this product alongside a standard multivitamin is generally safe, but the active forms in this product may make the multivitamin's B12 and folate redundant. Read both labels and decide which to keep.
MTHFR gene variant: Adults with documented MTHFR C677T or A1298C variants benefit specifically from L-5-MTHF (active folate) over folic acid. This product is the better choice if you have a confirmed variant.
Vegan and vegetarian readers: This is the right product for you. B12 in plant foods is essentially absent — supplementation is not optional for long-term vegan health. D3 from sun exposure is unreliable for indoor lifestyles regardless of latitude.
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